Welcome to issue #1.
You’re busy, the timeline is noisy, and you don’t need fifty press-release rewrites. Here’s what actually moved in AI this week (Nov 3–9, 2025) — across research, industry, and regulation — with just enough context that you can sound dangerous in a meeting.
🚀 The Big Story: Microsoft’s ‘Vertical Superintelligence’ Play
This week’s biggest signal wasn’t a new model, it was a new strategy. Microsoft announced the MAI Superintelligence Team, led by heavy-hitters Mustafa Suleyman and Karen Simonyan.

Their stated goal is not a god-like AGI. Instead, they’re targeting domain-specific superintelligence—systems that can outperform the best human experts in a single, high-value field.
Their first target: Medicine.
Expect a massive spend on models tuned for radiology, preventive care, and molecular design. They’re branding this as “humanist” and “controllable,” which is smart PR, but the business logic is even smarter.
Why You Should Care: This is the pivot from “my chatbot is smart” to “my AI saves lives (and has an insane TAM).” Frontier labs are converging on high-value verticals (healthcare, law, materials science) where evaluation is clear, the problems are real, and customers will pay a premium for verifiable, superhuman performance.
📈 The Macro Trend: The Moat Gets Deeper
The other quiet-but-loud trend this week: AI infra & chips keep centralizing.

The ongoing mega-deals for custom accelerators and the cost of AI datacenter buildouts mean one thing: the price of “serious” frontier model training is drifting further out of reach for small labs.
The Takeaway: This makes open and efficient methods strategically critical. If you can’t afford a billion-dollar training run, your only move is to be smarter. That’s why we’re seeing a parallel explosion in:
- Distillation (teaching small models from big ones)
- Sparse architectures & MoE
- Retrieval-heavy models (that read from a database instead of “remembering” everything)
💸 AI Markets & Bubble Bubblings
The ‘AI Bubble’ Finally Shows Some Teeth
After a year of vertical-only charts, the AI stock rally actually flinched.

Heavyweights like Nvidia and AI-adjacent plays whipsawed as investors questioned how fast massive AI capex translates into actual profit.
Why You Should Care: This wasn’t just a random dip; it was a stress test. Markets are starting to demand:
- Real revenue from AI products
- A story beyond “we’re training something huge”
The Takeaway: The easy money phase for “AI for AI’s sake” is fading. Expect flight-to-quality: clear ROI, clear customers, clear moats.
🧠 Machine Learning & Neural Nets
The ‘Best Model’ Is a Myth
Independent benchmarks keep confirming the obvious: Claude Sonnet-class and GPT-class models trade spots at the top, with several open and closed models close behind.

Translation: Stop treating model choice like fandom. Pick like procurement:
- Latency
- Context window
- Data policy / deployment model
- Cost per 1K tokens
The End of the Prompt Goblin
We’re finally seeing serious pushback against “prompt engineering as magic.” The interesting work is in:
- Better datasets
- Reliable tool calling
- Verifiable reasoning layers
That’s the shift from prompt vibes → actual systems engineering.
Neuromorphic Hardware: Early Signals

Experimental neuromorphic designs (e.g., Loihi-style chips) hint at hardware that could one day support brain-like dynamics with far less energy than current GPU stacks.
Not tomorrow. But the direction of travel is clear: efficiency and structure over brute force.
💬 Natural Language Processing (NLP)
EMNLP 2025: Less Hype, More Work
Main threads:
- Efficiency (distillation, quantization, retrieval)
- Realistic multilingual and low-resource benchmarks
- Evaluating tool-using agents on tasks, not vibes
The Future Is Small + Local
Vendors are leaning into:
- On-device models for sensitive, low-latency tasks
- Large remote models only when strictly needed
If you’re designing systems in 2025 and everything routes to one giant external API by default, you’re already behind.
👁️ Computer Vision & Robotics
Vision Is a Feature, Not the Plot

Vision quietly sits inside multimodal systems now:
- Medical imaging
- Industrial inspection
- Robotics perception
“Cat detector” startups are over. Vision that plugs into decision-making pipelines is not.
Robots With “Good Enough” Brains
We’re seeing real pilots where:
- LLMs/VLMs plan tasks
- Classical control guarantees don’t-kill-anyone behavior
If your robotics stack treats the LLM like an oracle instead of one signal among many, that’s a safety bug, not a feature.
📊 Data Science & Ethics
Your Semantic Layer Is the Real Model

“Ask your data in English” only works if:
- Metrics are well-defined
- Tables and lineage are documented
Do the boring work. Every “AI analytics” tool is only as smart as your definitions.
The EU AI Act Blinks (But You Don’t)

The EU is floating grace periods and softened timelines, but:
- Obligations aren’t going away
- Enterprise buyers are already asking for:
- Training data transparency
- Evaluation reports
- Incident response plans
If your internal story is “we’ll fix compliance later,” you’re gambling with future procurement.
💸 The ‘So What?’ for People Who Ship
This week, condensed into operating principles:
- Vertical focus wins. Copy the “medical superintelligence” pattern into your domain.
- Model choice is procurement. Mix open/closed/local based on risk, latency, and cost.
- Governance is product. Evaluations, logs, deletion guarantees — these sell now.
If your AI roadmap doesn’t mention evaluation, monitoring, or data boundaries, it’s not a roadmap.
It’s fanfic.